BDBM396098 US10308663, JMS-557-038::US12227515, Compound JMS-038

SMILES O=c1[nH]c2sc(cc2c(=O)[nH]1)-c1ccccc1

InChI Key InChIKey=SBSYHISFNMCGGV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 396098   

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 2.50E+5nMAssay Description:The in vitro biochemical evaluation of all compounds was carried out using recombinant human PTP4A3, overexpressed as a His6-tag fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent