BDBM385389 (3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]pyrimidin-2-yl]pyrrolidin-3-ol; Dihydrochloride::US10287270, Example 6::US10464928, Example 6::US10793552, Example 6

SMILES NC\C(COc1cnc(nc1)N1CC[C@H](O)C1)=C/F

InChI Key InChIKey=PGWHLRYXOSBDBE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 385389   

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
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TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 52nMAssay Description:Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo assay kit from Promega (V1402). Test compounds (wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Eli Lilly

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2025
Entry Details
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TargetAmine oxidase [copper-containing] 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 1.12E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2025
Entry Details
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TargetDiamine oxidase [copper-containing](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM385389((3 S)-1-[5-[(E)-2-(Aminomethyl)-3-fluoro-allyloxy]...)
Affinity DataIC50: 1.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent