BDBM50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232

SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C

InChI Key InChIKey=BTOJYCTUJJHANF-UHFFFAOYSA-N

Data  19 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50041961   

TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  4nMAssay Description:Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  4.20nMAssay Description:Tested in vitro for the inhibition of [3H]U-86170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  13nMAssay Description:Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]U-86170More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  13nMAssay Description:Binding affinity against human Dopamine receptor D3 in Chinese hamster ovary cells using [3H]spiperone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  13nMAssay Description:Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  15nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]U-86170)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  15nMAssay Description:Tested in vitro for the inhibition of [3H]raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  18nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  22nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  48nMAssay Description:Tested in vitro for the inhibition of [3H]spiperone binding to Dopamine receptor D4, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  48nMAssay Description:Binding affinity was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetD(4) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  48nMAssay Description:Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  63nMAssay Description:Binding affinity against human Dopamine receptor D2 in mouse LtK- cells using [3H]spiperone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2018
Entry Details

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  70nMAssay Description:Binding towards Dopamine receptor D2 using [3H]spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  100nMAssay Description:Evaluated for binding towards dopamine D2-receptor using [3H]N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  168nMAssay Description:Tested in vitro for the inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target5-hydroxytryptamine receptor 5A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  168nMAssay Description:Binding affinity was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]8-OH-DPAT )More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50041961((5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-...)
Affinity DataKi:  228nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed