BDBM50169774 2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; compound with methanesulfonic acid::CHEMBL360943::U-50488H::U50,488H

SMILES CN(C1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=VQLPLYSROCPWFF-UHFFFAOYSA-N

Data  23 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50169774   

TargetKappa-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Biological Research Center of Hungarian Academy of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  220nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  279nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Rat)
Biological Research Center of Hungarian Academy of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  288nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  294nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  304nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetNeuropeptides B/W receptor type 1(Human)
Addiction Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  610nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2011
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  1.35E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetDelta-type opioid receptor(Pig)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi:  2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Pig)
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Targetkappa-type opioid receptor isoform 1(Western clawed frog)
Biological Research Center of Hungarian Academy of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50169774(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed