BDBM50059891 1-amino-2-(3,4,5-trimethoxyphenyl)ethane::2-(3,4,5-trimethoxyphenyl)ethanamine::3,4,5-trimethoxybenzeneethanamine::3,4,5-trimethoxyphenethylamine::3,4,5-trimethoxyphenylethylamine::CHEMBL26687::Mescalin::Meskalin::TMPEA::US20240166618, Compound Mescaline::mescalina::mescaline::mezcalina

SMILES COc1cc(CCN)cc(OC)c1OC

InChI Key InChIKey=RHCSKNNOAZULRK-UHFFFAOYSA-N

Data  62 KI  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 72 hits for monomerid = 50059891   

Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  118nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  208nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  114nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  87.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  1.13E+4nMAssay Description:Activity at rat 5HT2A receptor assessed as 5-HT-stimulated IP3 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  2.60E+3nMAssay Description:Tested for its ability to activate phospholipase c by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  2.40E+4nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  303nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]DOI radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  380nMAssay Description:Displacement of [125I]DOI from rat 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  551nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]DOI radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  745nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  793nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  795nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  1.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetNischarin(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  2.68E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  5.21E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  5.50E+3nMAssay Description:Ability to displace [3H]ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  6.90E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  8.93E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetVasopressin V1b receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Bovine)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Oklahoma

LigandPNGBDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMed
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