BDBM50290077 CHEMBL73416::N-[2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridin-3-ylmethyl]-N-methyl-butyramide::Saripidem

SMILES CCCC(=O)N(C)Cc1c(nc2ccccn12)-c1ccc(Cl)cc1

InChI Key InChIKey=LIFDPEORUVTOCP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290077   

LigandPNGBDBM50290077(N-[2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridin-3-ylm...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of [3H]-Flumazenil binding to recombinant GABA-A receptor alpha-5 subunit in spinal cordMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50290077(N-[2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridin-3-ylm...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-5 subunit in cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50290077(N-[2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridin-3-ylm...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50290077(N-[2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridin-3-ylm...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]flumazenil binding to recombinant GABA-A receptor alpha-1-beta-2-gamma-2 subunitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article