BDBM50090676 (+-)-2-(p-(2-thenoyl)phenyl)propionic acid::2-(4-(2-Thenoyl)phenyl)propionsaeure::2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid::4-(2-Thenoyl)hydratropsaeure::CHEMBL956::SUPROFEN::alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid::p-2-thenoylhydratropic acid

SMILES CC(C(O)=O)c1ccc(cc1)C(=O)c1cccs1

InChI Key InChIKey=MDKGKXOCJGEUJW-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50090676   

TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataIC50: 560nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataKi:  1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataKi:  3.70E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataKi:  8.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataKi:  8.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50090676(2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid ...)
Affinity DataKi:  4.50E+4nMAssay Description:Binding affinity measured on human cytochrome P450 2C9 (CYP2C9) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed