BDBM50297446 CHEMBL561604::N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamide::ST-5732

SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O

InChI Key InChIKey=VSVDNXSUROYWOP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50297446   

TargetHistone deacetylase 1(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human HDAC1 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human HDAC2 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human HDAC3 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human HDAC4 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human HDAC5 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC6 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human HDAC7 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human HDAC8 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human HDAC9 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sigma-Tau Research and Development

Curated by ChEMBL
LigandPNGBDBM50297446(N-hydroxy-7,7-bis(5-nitro-1H-indol-3-yl)heptanamid...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human HDAC10 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed