BDBM163631 SR-3213::US10807944, Compound RLS2-138::US11731934, Compound RLS2-138

SMILES Brc1ccc(cc1)C(=O)NNCCc1ccccc1

InChI Key InChIKey=PHEVVCRULNVOLA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 163631   

TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Human)
University of Florida College of Medicine

LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395 498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Human)
University of Florida College of Medicine

LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395 498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Human)
University of Florida College of Medicine

LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 2.42E+4nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395 498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM163631(SR-3213 | US10807944, Compound RLS2-138 | US117319...)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent