BDBM50225188 (2-(2-amino-6-oxo-1,6,7,8-tetrahydropurin-9-yl)ethoxy)methylphosphonate::4-Fluoro-phenol::4-fluorophenol::CHEMBL559509::CHEMBL56226::SR-1C10

SMILES Nc1nc2N(CCOCP(O)(O)=O)CNc2c(=O)[nH]1

InChI Key InChIKey=WWAFBNZVNGXNRH-UHFFFAOYSA-N

Data  2 KI  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225188   

TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50225188(CHEMBL56226 | 4-Fluoro-phenol | CHEMBL559509 | 4-f...)
Affinity DataKi:  2.90E+4nMpH: 7.4Assay Description:Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50225188(CHEMBL56226 | 4-Fluoro-phenol | CHEMBL559509 | 4-f...)
Affinity DataKi:  5.59E+4nMpH: 8.5Assay Description:Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50225188   

HostPNGBDBM36284(SAMPL3, H3 | BDBM36303 | Methyl Viologen-Cucurbit[...)
University of Cambridge

GuestPNGBDBM50225188(CHEMBL56226 | 4-Fluoro-phenol | CHEMBL559509 | 4-f...)
ITC DataΔG°: -5.23kcal/mole logk: 6.80E+3
pH: 7.0 T: 25.00°C