BDBM50590443 SECLIDEMSTAT::SP-2577::SP2577::Seclidemstat::Sp-2577

SMILES CN1CCN(CC1)S(=O)(=O)c1cccc(c1)C(=O)N\N=C(/C)c1cc(Cl)ccc1O

InChI Key InChIKey=MVSQDUZRRVBYLA-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50590443   

TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataIC50: 127nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3K4me2 peptide as substrate incubated for 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50590443(Seclidemstat | Sp-2577 | SP-2577 | SP2577 | SECLID...)
Affinity DataKi:  31nMAssay Description:Inhibition of LSD1 (unknown origin) assessed as inhibition constant by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed