BDBM231638 SM19712

SMILES Cc1[nH]nc(NC(=O)[N-]S(=O)(=O)c2ccc(Cl)cc2)c1C#N

InChI Key InChIKey=DXDDYHCYMXTLIY-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 231638   

TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM231638(SM19712)
Affinity DataIC50: 5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM231638(SM19712)
Affinity DataIC50: 1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM231638(SM19712)
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed