BDBM50375643 CHEMBL261237::SL-327

SMILES Nc1ccc(SC(=N)C(C#N)c2ccccc2C(F)(F)F)cc1

InChI Key InChIKey=XQRVCODIGHFXKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375643   

TargetTranscription factor Jun(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375643(SL-327 | CHEMBL261237)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of AP1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375643(SL-327 | CHEMBL261237)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375643(SL-327 | CHEMBL261237)
Affinity DataIC50: 220nMAssay Description:Inhibition of MEK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375643(SL-327 | CHEMBL261237)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed