BDBM50289464 3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[cyclopentane-1,7'-(4',5',7',8'-tetrahydro-3'H-imidazo[2,1-b]purine)]-4'-one::CHEMBL28676::SCH-57726

SMILES CN1C2=NC3(CCCC3)CN2c2nc(-c3ccc(cc3)C3CCCCC3)n(Cc3ccccc3)c2C1=O

InChI Key InChIKey=COWBACSJPXQWNS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289464   

TargetPhosphodiesterase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine heart phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 190nMAssay Description:Inhibition of bovine lung phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine aorta phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article