BDBM50306874 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',5':4,5]benzo[1,2,3-cd]indol-5-one::CHEMBL609040::SCH-535270

SMILES Oc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13

InChI Key InChIKey=OVACCXPNQSWBBB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306874   

TargetCyclin-dependent kinase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(SCH-535270 | 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',...)
Affinity DataIC50: 214nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(SCH-535270 | 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(SCH-535270 | 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306874(SCH-535270 | 8-Hydroxy-6H-benzo[f][1,3]dioxolo[4',...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed