BDBM50306888 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline::CHEMBL603097::SCH-47089

SMILES COc1ccc2nc3[nH]nc(C)c3c(OC)c2c1

InChI Key InChIKey=AWSLSQGTMWLKRH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306888   

TargetCyclin-dependent kinase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(SCH-47089 | 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(SCH-47089 | 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(SCH-47089 | 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(SCH-47089 | 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of AUR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50306888(SCH-47089 | 4,6-dimethoxy-3-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed