BDBM50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116
SMILES COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12
InChI Key InChIKey=GAYSOZKZPOVDSB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 37 hits for monomerid = 50005833
Affinity DataEC50: 23nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity against 5-HT4 receptor in rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to adrenergic beta-1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 23.7nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay of racemate mixtureMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to adrenergic beta-2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to adrenergic alpha-2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Displacement of [3H]GR65630 from 5HT3 receptor in brain cortex from Wistar ratMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Compound was tested for 5-hydroxytryptamine 3 receptor binding affinityMore data for this Ligand-Target Pair
Affinity DataKi: 152nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for alpha-2 adrenergic receptor bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for 5-hydroxytryptamine 2 receptor bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Beta adrenergic receptor bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for 5-hydroxytryptamine 1 receptor bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity of compound towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for alpha-1 adrenergic receptor bindingMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
Searle Research and Development
Curated by ChEMBL
Searle Research and Development
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Dopamine receptor D1 bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for Dopamine receptor D2 bindingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair