BDBM706140 SB-FAP-10::US20240382629, Example vi

SMILES [H]c1ccc(OC2=C(/C=C/C3[NH+](CCCCCC(=O)N[C@@H](CCCCn4cc(CCC(=O)NCCCOc5cccc(/C(=CC=N)C(=O)NCC(=O)N6CCCC6C#N)c5)nn4)C(=O)NCCNC(=O)CCC(C(=O)O)N4CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC4)c4ccc(C)cc4C3(C)C)CCC/C2=CC=C2N(CCCCS(=O)(=O)O)c3ccc([H])cc3C2(C)C)cc1

InChI Key

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 706140   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706140(SB-FAP-10 | US20240382629, Example vi)
Affinity DataIC50: 1.19E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706140(SB-FAP-10 | US20240382629, Example vi)
Affinity DataIC50: 2.53E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706140(SB-FAP-10 | US20240382629, Example vi)
Affinity DataIC50: 3.43nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706140(SB-FAP-10 | US20240382629, Example vi)
Affinity DataKi:  0.690nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent