BDBM706138 SB-FAP-06::US20240382629, Example iv

SMILES [H]C(CCCCN(Cc1ccc(Br)cc1)C(=O)CCCCCNC(=O)[C@H](CCCCn1cc(CCC(=O)NCCCOc2ccc3nccc(C(=O)NCC(=O)N4CCC[C@H]4C#N)c3c2)nn1)NC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)NC(=O)N[C@@H](CCC(=O)O)C(=O)O

InChI Key InChIKey=ZUEXRXMHJQFNSG-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 706138   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataIC50: 1.41E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataIC50: 370nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataIC50: 1.84nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataIC50: 4.71nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706138(SB-FAP-06 | US20240382629, Example iv)
Affinity DataKi:  0.940nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent