BDBM706142 SB-FAP-04::US20240382629, Example viii

SMILES CC1(C)/C(=CC=C2/CCCC(/C=C/C3[NH+](CCCCCC(O)NCCCC[C@H](NC(=O)CCOCCOCCOCCn4cc(CCC(=O)NCCCOc5ccc6nccc(C(=O)NCC(=O)N7CCC[C@H]7C#N)c6c5)nn4)C(=O)NCCCCC(=O)N(CCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)Cc4ccc(Br)cc4)c4ccc(S(=O)(=O)[O-])cc4C3(C)C)=C2Oc2ccc(S(=O)(=O)O)cc2)N(CCCCS(=O)(=O)O)c2ccc(S(=O)(=O)O)cc21

InChI Key

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 706142   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataIC50: 4.93E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataIC50: 1.27E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataIC50: 3.76nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataIC50: 26.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataKi:  0.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706142(SB-FAP-04 | US20240382629, Example viii)
Affinity DataKi:  5.33nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent