BDBM50130279 (R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)::4-Methyl-1-{2-[(R)-1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::4-Methyl-1-{2-[(S)-1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::4-Methyl-1-{2-[1-(toluene-3-sulfonyl)-pyrrolidin-2-yl]-ethyl}-piperidine::CHEMBL12624::SB-258741

SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(C)c2)CC1

InChI Key InChIKey=YVWGGGGMRDLOGA-UHFFFAOYSA-N

Data  20 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50130279   

Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards rat 5-HT7 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Antagonist activity at 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human 5-HT7 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.58E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  1.58E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  2.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.16E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  3.16E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  5.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi:  5.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50130279((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed