BDBM50271179 2-(2-(quinolin-2-yl)vinyl)phenol::CHEMBL487942::S136492

SMILES Oc1ccccc1\C=C/c1ccc2ccccc2n1

InChI Key InChIKey=NXNDEWNGCMCWMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271179   

TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: 1.60E+3nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: 1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: 4.63E+3nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed