BDBM50346866 CHEMBL1797643::S1201

SMILES NC1CC1c1cccc(F)c1OCc1ccccc1

InChI Key InChIKey=UQQFXBLESPXLHL-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50346866   

TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataIC50: 8.10E+3nMAssay Description:The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of hexahistidine-tagged LSD1 (unknown origin) (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of hexahistidine-tagged human LSD1 (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptide as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Systems and Structural Biology Center

LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of hexahistidine-tagged LSD1 (unknown origin) (172 to 833 residues) expressed in Escherichia coli Rosetta (DE3) cells using H3K4me2 peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of human MAO-B expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of human recombinant MAO-B using tyramine as substrate assessed as inhibition constant by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of human MAO-A expressed in expressed in baculovirus infected BTI insect cells using tyramine as substrate by peroxidase-coupled methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50346866(CHEMBL1797643 | S1201)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of human recombinant MAO-A using tyramine as substrate assessed as inhibition constant by peroxidase-coupled reaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed