BDBM50101969 3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy}-benzofuran-2-carboxylic acid ethyl ester::CHEMBL301315::Ro-09-4609

SMILES CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C

InChI Key InChIKey=WVIFNQSMGQMTKX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101969   

TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human N-myristoyltransferase using [3H]-myristoyl-CoA and GLYVSRLFNRLFQKK(Biotin)-NH2 as substrate after 30 mins scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 5.40E+5nMAssay Description:Inhibitory activity against human N-myristoyltransferase (HsNmt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Candida albicans N-myristoyltransferase (CaNmt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (HsNmt) assessed as inhibitory concentration using substrate peptide and myristotyl-CoA at 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2018
Entry Details Article
PubMed