BDBM50088706 CHEMBL12062::N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-propyl}-2-(2-oxo-piperidin-1-yl)-acetamide::RWJ-69736

SMILES CC(C)Oc1ccccc1N1CCN(CCCNC(=O)CN2CCCCC2=O)CC1

InChI Key InChIKey=STMYXSKGGILJBE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088706   

TargetAlpha-1A adrenergic receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50088706(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  0.650nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50088706(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  0.660nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088706(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  80nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088706(N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed