BDBM50240410 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine::3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine::5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine::5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine::CHEMBL644::RP-7162::Sapilent::TRIMIPRAMINE::Trimeprimine::beta-methylimipramine::trimeproprimine

SMILES CC(CN(C)C)CN1c2ccccc2CCc2ccccc12

InChI Key InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50240410   

TargetSolute carrier family 22 member 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataKi:  149nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataKi:  2.45E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50240410(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2...)
Affinity DataKi:  3.78E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed