BDBM50093526 CHEMBL426373::RK-682

SMILES CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@@H](CO)OC1=O

InChI Key InChIKey=KZTSLHQKWLYYAC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50093526   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant PTP1B pre-incubated for 10 mins before pnitrophenyl phosphate substrate addition and measured every 30 secs for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human PTP1B preincubated for 10 mins followed by protein addition using pNPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHeparanase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed