BDBM18699 (2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide::CHEMBL296323::R-3

SMILES C[C@](O)(CBr)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=QDSWNDMHSBZXKX-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18699   

TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.300nM ΔG°:  -12.1kcal/mole EC50:  500nMpH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against human androgen receptor (hAR) in competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.300nMAssay Description:Agonist activity at androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.302nMAssay Description:Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed