BDBM50097224 1-Methyl-4-thioxanthen-9-ylidene-piperidine::1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine::CHEMBL152408::Pimethixene

SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccccc2-[#16]-c2ccccc-12

InChI Key InChIKey=SRJGFZTWQAHZMK-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097224   

TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Insa

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of LuxR-dependent quorum sensing in Vibrio fischeri assessed as reduction of 3-oxo-C6-HSL-induced bioluminescence intensityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor from rat forebrain using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097224(1-Methyl-4-thioxanthen-9-ylidene-piperidine | Pime...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed