BDBM53406 (6Z)-1-benzoyl-4-(4-fluorobenzyl)-5-(4-methoxyphenyl)-5,8-dihydro-2H-1,4-diazocin-3-one::(6Z)-1-benzoyl-4-[(4-fluorophenyl)methyl]-5-(4-methoxyphenyl)-5,8-dihydro-2H-1,4-diazocin-3-one::(6Z)-4-[(4-fluorophenyl)methyl]-5-(4-methoxyphenyl)-1-(phenylcarbonyl)-5,8-dihydro-2H-1,4-diazocin-3-one::MLS000863187::PiH::SMR000465277::cid_16746512

SMILES COc1ccc(cc1)C1\C=C/CN(CC(=O)N1Cc1ccc(F)cc1)C(=O)c1ccccc1

InChI Key InChIKey=ZIQYJOMMLGKHMO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 53406   

TargetPeptidyl-prolyl cis-trans isomerase ESS1(Baker's yeast)
Tohoku University

LigandPNGBDBM53406(cid_16746512 | (6Z)-4-[(4-fluorophenyl)methyl]-5-(...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:Assay was carried out measuring the MCA fluorescence using Suc-Ala-Glu-Pro-Phe-MCA as substrate purchased from Japan Peptide Institute Co.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53406(cid_16746512 | (6Z)-4-[(4-fluorophenyl)methyl]-5-(...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay