BDBM50071549 CHEMBL309056::N-[(S)-(1-Benzyl-3-butylcarbamoyl-2-hydroxy-propylcarbamoyl)-phenyl-methyl]-2,4-dimethoxy-benzamide::PS-154636-1::PS-154636-2

SMILES CCCCNC(=O)CC(O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc(OC)cc1OC)c1ccccc1

InChI Key InChIKey=SXBWRHFAOQVOPG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071549   

TargetPlasmepsin II(Plasmodium falciparum)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50071549(PS-154636-2 | N-[(S)-(1-Benzyl-3-butylcarbamoyl-2-...)
Affinity DataKi:  590nMAssay Description:In vitro inhibition of plasmepsin-2 from Plasmodium falciparum.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin D(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50071549(PS-154636-2 | N-[(S)-(1-Benzyl-3-butylcarbamoyl-2-...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin D(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50071549(PS-154636-2 | N-[(S)-(1-Benzyl-3-butylcarbamoyl-2-...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50071549(PS-154636-2 | N-[(S)-(1-Benzyl-3-butylcarbamoyl-2-...)
Affinity DataKi: >3.00E+4nMAssay Description:In vitro inhibition of plasmepsin-2 from Plasmodium falciparum.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed