BDBM50013720 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine::CHEMBL65063::PP3::cid_4879

SMILES Nc1ncnc2n(ncc12)-c1ccccc1

InChI Key InChIKey=KKDPIZPUTYIBFX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50013720   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50013720(CHEMBL65063 | PP3 | cid_4879 | 1-Phenyl-1H-pyrazol...)
Affinity DataIC50: 2.11E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50013720(CHEMBL65063 | PP3 | cid_4879 | 1-Phenyl-1H-pyrazol...)
Affinity DataIC50: 2.05E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013720(CHEMBL65063 | PP3 | cid_4879 | 1-Phenyl-1H-pyrazol...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
University of Dundee

Curated by PDSP Ki Database
LigandPNGBDBM50013720(CHEMBL65063 | PP3 | cid_4879 | 1-Phenyl-1H-pyrazol...)
Affinity DataKi:  9.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50013720(CHEMBL65063 | PP3 | cid_4879 | 1-Phenyl-1H-pyrazol...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity (Ki) against human phosphatidylinositol 4-kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed