BDBM83449 1-(1-phenylcyclohexyl)piperidine;hydrochloride::MLS002320664::PCP::PCP hydrochloride::PHENCYCLIDINE::Phencyclidine hydrochloride::SMR001338811::cid_9795678
SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1
InChI Key InChIKey=JTJMJGYZQZDUJJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 36 hits for monomerid = 83449
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 868nMAssay Description:Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition activity against binding of phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Human)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 3.36E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Affinity DataKd: 9.10E+3nMAssay Description:Dissociation constant towards Muscarinic acetylcholine receptor was determined by using [3H]4NMPB as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Glaxosmithkline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of specific binding of [3H]NANM of sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
Affinity DataKi: 53nMAssay Description:Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
Affinity DataKi: 65nMAssay Description:Compound was evaluated for its ability to displace [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor in rat brainMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
Affinity DataKi: 91nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
Affinity DataKi: 520nMAssay Description:Compound was evaluated for the protection of butyrylcholinesterase against DFT in miceMore data for this Ligand-Target Pair
Affinity DataKi: 525nMAssay Description:Compound was evaluated for the protection of butyrylcholinesterase against DFT in mice and expressed as Ki.More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
The Johns Hopkins University
Curated by PDSP Ki Database
The Johns Hopkins University
Curated by PDSP Ki Database
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago
Curated by ChEMBL
University of Illinois At Chicago
Curated by ChEMBL
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 1.09E+3nMAssay Description:Compound was evaluated for its ability to displace [3H](+)-pentazocine from sigma receptor in Guinea pig brainMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse
Curated by ChEMBL
National Institute On Drug Abuse
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Affinity DataKi: 1.00E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2B6More data for this Ligand-Target Pair