BDBM50145829 4-Aminobenzoesaeure::4-aminobenzoic acid::CHEMBL542::PABA::p-Aminobenzoesaeure::p-aminobenzoic acid::para-aminobenzoic acid

SMILES Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=ALYNCZNDIQEVRV-UHFFFAOYSA-N

Data  6 IC50  2 Kd

PDB links: 14 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50145829   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataKd: >4.00E+4nMAssay Description:Dissociation constant for HCV NS3 protease substrate binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSuccinate-semialdehyde dehydrogenase, mitochondrial(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against SSADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against GABATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
Whittier College

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli DH5aplha cells assessed as O-deethylation of ethoxyresorufin in presence of NADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetDihydropteroate synthase(Bacillus anthracis)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataKd:  5.62E+3nMAssay Description:Binding affinity to Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 35.2nMAssay Description:Inhibition of AChE activity in rat brain homogenate using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50145829(4-aminobenzoic acid | 4-Aminobenzoesaeure | PABA |...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed