BDBM50087272 CHEMBL34155::P4S::Piperidine-4-sulfonic acid::Piperidine-4-sulfonic acid (P4S)

SMILES OS(=O)(=O)C1CCNCC1

InChI Key InChIKey=UGBJGGRINDTHIH-UHFFFAOYSA-N

Data  7 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50087272   

TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  6.50E+4nMAssay Description:Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  2.00E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  4.00E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  2.00E+5nMAssay Description:Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  2.60E+4nMAssay Description:Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataEC50:  2.00E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  39.8nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  58.9nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  72.4nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  91.2nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  97.7nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  107nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Affinity DataKi:  151nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed