BDBM50404388 P 276-00 free base::P-276-00 free base::P276-00::RIVICICLIB::Riviciclib

SMILES CN1CCC(C1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key InChIKey=IFLRPOIEUGFXQU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404388   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CDK9/cyclin T1 in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human CDK1/Cyclin B in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 224nMAssay Description:Inhibition of human CDK2/Cyclin A in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human CDK4/Cyclin D1 assessed as substrate phosphorylation at ser780 using GST tagged retinoblastoma as substrate in presence of gamma3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50404388(RIVICICLIB | Riviciclib | P 276-00 free base | P-2...)
Affinity DataIC50: 396nMAssay Description:Inhibition of human CDK6/Cyclin D3 in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed