BDBM50403163 OXITRIPTAN

SMILES c1cc2c(cc1O)c(c[nH]2)C[C@@H](C(=O)O)N

InChI Key InChIKey=LDCYZAJDBXYCGN-UHFFFAOYSA-N

Data  4 KI  8 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50403163   

Target5-hydroxytryptamine receptor 2A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  130nMAssay Description:Agonist activity at 5-HT2A receptor (unknown origin) expressed in HEK293 cell membranes assessed as induction of [35S]-GTPgammaS binding incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  0.219nMAssay Description:Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  0.219nMAssay Description:Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  1.29nMAssay Description:Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  1.35nMAssay Description:Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataEC50:  9.80nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]-5-HT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cell membranes incubated for 15 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT7 receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
LigandPNGBDBM50403163(OXITRIPTAN)
Affinity DataKi:  158nMAssay Description:Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article