BDBM50189778 CHEMBL211405::N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide::ORG-41841::cid_9887381

SMILES COc1cccc(c1)-c1nc(SC)nc2sc(C(=O)NC(C)(C)C)c(N)c12

InChI Key InChIKey=DVSFSADBOJYPGF-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50189778   

TargetSentrin-specific protease 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataIC50: 1.52E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSentrin-specific protease 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataIC50: 1.91E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetLutropin-choriogonadotropic hormone receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyrotropin receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at TSHR expressed in HEK293 EM cells measured by intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C11(Rat)
Nih Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  7.70E+3nMAssay Description:Agonist activity at TSHR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLutropin-choriogonadotropic hormone receptor(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50189778(cid_9887381 | N-tert-butyl-5-amino-4-(3-methoxyphe...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at LHCGR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed