BDBM50075822 (S)-N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-3-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-succinamic acid tert-butyl ester::CHEMBL329908::N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-3-((S)-4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-succinamic acid tert-butyl ester::ORG-37476

SMILES COc1cc(C)c(c(C)c1C)S(=O)(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)NC(Cc1ccc2c(N)nccc2c1)C(=O)N1CCCCC1

InChI Key InChIKey=PTDUDCRDRXTZTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075822   

TargetSerine protease 1(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822(ORG-37476 | N-[1-(1-Amino-isoquinolin-6-ylmethyl)-...)
Affinity DataIC50: 3.78E+5nMAssay Description:In vitro trypsin inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822(ORG-37476 | N-[1-(1-Amino-isoquinolin-6-ylmethyl)-...)
Affinity DataIC50: 80nMAssay Description:In vitro thrombin inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822(ORG-37476 | N-[1-(1-Amino-isoquinolin-6-ylmethyl)-...)
Affinity DataIC50: 82nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822(ORG-37476 | N-[1-(1-Amino-isoquinolin-6-ylmethyl)-...)
Affinity DataIC50: 3.78E+5nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed