BDBM50037382 5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid::5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-phenyl)-hex-5-enyloxy]-phenoxy}-pentanoic acid (ONO-4057)::CHEMBL422420::ONO 4057::ONO-4057

SMILES COc1ccc(\C=C\CCCCOc2cccc(OCCCCC(O)=O)c2CCC(O)=O)cc1

InChI Key InChIKey=JOPSSWGWLCLPPF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50037382   

TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  3.70nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  4nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]LTB4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  4nMAssay Description:Binding affinity against LTB4 receptors in human PMNs using [3H]LTB4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sultan Moulay Slimane University

Curated by ChEMBL
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  4nMAssay Description:Antagonist activity against LTB4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetLeukotriene B4 receptor 2(Human)
The University of Tokyo

Curated by PDSP Ki Database
LigandPNGBDBM50037382(ONO 4057 | 5-{2-(2-Carboxy-ethyl)-3-[6-(4-methoxy-...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMed