BDBM25392 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride::4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol::4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2::CHEMBL434::ISOPROTERONOL::Isoprenaline::Isoproterenol::Isoproterenol (-)::Isoproterenol,(+)::Isoproterenol-l::Norisodrine::Novodrin
SMILES CC(C)NCC(O)c1ccc(O)c(O)c1
InChI Key InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 151 hits for monomerid = 25392
Affinity DataKd: 200nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 58nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:In vitro beta-adrenergic activity against beta-1 adrenergic receptor by the inhibition of insulin stimulated [14C]- glucose incorporation into glycog...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:In vitro beta adrenergic receptor activity against beta-3 adrenergic receptor in rat epididymal fat pads by stimulation of glycerol release from adip...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for its binding affinity towards beta-2 adrenergic receptor in rat soleus membrane by displacing (-)-isoproterenol (50 uM)More data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human adrenergic beta-3 receptor expressed in CHO cells assessed as cAMP levels by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human cloned beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-ga...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-ga...More data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation by beta-g...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
Affinity DataEC50: 129nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in DU145 cells assessed as increase in cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.970nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as induction of intracellular cAMP accumulation after...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmuno...More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.840nMAssay Description:Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme imm...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity against human beta 1 adrenergic receptor (AR), expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Activity against human beta 3 adrenergic receptor (AR), expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Activity against human beta 2 adrenergic receptor (AR), expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as intracellular cAMP accumulation after 1 hrMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human beta2 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Agonist activity at adrenergic beta2 receptor in Hartley guinea pig tracheal ring assessed as bronchorelaxation activity against histamine-induced co...More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Agonist activity at adrenergic beta2 receptor in Hartley guinea pig tracheal ring at basal tone assessed as bronchorelaxation activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 86nMAssay Description:Agonist activity at human recombinant beta3-adrenergic receptor expressed in CHO cells assessed as increase of cAMP level after 30 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.970nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.970nMAssay Description:Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0840nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.970nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.840nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at PK-tagged beta2 receptor (unknown origin) transfected in HEK293 cells after 90 mins by beta-arrestin assayMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Agonist activity at human beta2 receptor expressed in HEK293 cells cotransfected with Gqs5 protein assessed as [3H]IP3 accumulation after 120 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist efficacy for human Beta-3 adrenergic receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Concentration required to effect a 50% relaxation of rat ferret detrusor basal toneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair