BDBM50470664 Netilmicin

SMILES CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O

InChI Key InChIKey=CIDUJQMULVCIBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50470664   

TargetPhospholipase A1 member A(Rat)
Agricultural University of Athens

Curated by ChEMBL
LigandPNGBDBM50470664(Netilmicin)
Affinity DataIC50: 1.15E+5nMAssay Description:IC50 was measured as concentration causing 50% inhibition of lysosomal phospholipase A1 activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50470664(Netilmicin)
Affinity DataIC50: 8.00E+6nMAssay Description:Inhibition of TDP1 (unknown origin) using 14-mer duplex oligonucleotide [32P]-D14Y as substrate incubated for 20 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed