BDBM81486 CAS_1050-79-9::MOPERONE::NSC_4249

SMILES Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=AGAHNABIDCTLHW-UHFFFAOYSA-N

Data  14 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 81486   

TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKd:  0.955nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKd:  0.955nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  0.724nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  0.724nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
In Depth
Date in BDB:
3/3/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  880nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetD(1A) dopamine receptor(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81486(NSC_4249 | CAS_1050-79-9 | MOPERONE)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed