BDBM348885 NSC8676::US9791447, Compound SPI-03

SMILES Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S([O-])(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O

InChI Key InChIKey=UVHHADIQQIICAV-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 348885   

TargetSentrin-specific protease 1(Human)
City of Hope

US Patent
LigandPNGBDBM348885(NSC8676 | US9791447, Compound SPI-03)
Affinity DataIC50: 3.80E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSentrin-specific protease 2(Human)
City of Hope

US Patent
LigandPNGBDBM348885(NSC8676 | US9791447, Compound SPI-03)
Affinity DataIC50: 2.40E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetSentrin-specific protease 7(Human)
City of Hope

US Patent
LigandPNGBDBM348885(NSC8676 | US9791447, Compound SPI-03)
Affinity DataIC50: 4.80E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent