BDBM50342003 CHEMBL501993::NSC-87877::disodium 8-hydroxy-7-[(E)-(6-sulfonato-2-naphthyl)diazenyl]quinoline-5-sulfonate::sodium 8-hydroxy-7-((6-sulfonatonaphthalen-2-yl)diazenyl)quinoline-5-sulfonate

SMILES Oc1c(cc(c2cccnc12)S([O-])(=O)=O)N=Nc1ccc2cc(ccc2c1)S([O-])(=O)=O

InChI Key InChIKey=XGMFVZOKHBRUTL-UHFFFAOYSA-L

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50342003   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342003(NSC-87877 | disodium 8-hydroxy-7-[(E)-(6-sulfonato...)
Affinity DataIC50: 320nMAssay Description:Inhibition of SHP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342003(NSC-87877 | disodium 8-hydroxy-7-[(E)-(6-sulfonato...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human 6his-tagged SHP2 (2 to 593 residues) expressed in Escherichia coli BL21 Star (DE3) cells preincubated with IRS1_pY1172(dPEG8)pY12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342003(NSC-87877 | disodium 8-hydroxy-7-[(E)-(6-sulfonato...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 20 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342003(NSC-87877 | disodium 8-hydroxy-7-[(E)-(6-sulfonato...)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant SHP2 (262 to 532 amino acids) (unknown origin) incubated for 1 hr using 10 uM DiFMUP by DiFMUP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed