BDBM50332182 4,3',5'-tri-O-methylpiceatannol::5-(2-(3,5-Dimethoxyphenyl)vinyl)-2-methoxyphenol::5-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-phenol::5-[2-(3,5-Dimethoxy-phenyl)-vinyl]-2-methoxy-phenol::CHEMBL419378::NSC-381864::US11866416, Example 9

SMILES COc1cc(OC)cc(\C=C\c2ccc(OC)c(O)c2)c1

InChI Key InChIKey=UQIWTPQGJCCTPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332182   

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester and Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50332182(4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant NQO2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester and Manchester Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50332182(4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Campania "L. Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50332182(4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...)
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of human 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Campania "L. Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50332182(4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of 5-LOX in human PMNL cells assessed as A23187-stimulated LTB4 production preincubated for 15 mins followed by A23187 addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50332182(4,3',5'-tri-O-methylpiceatannol | 5-(2-(3,5-Dimeth...)
Affinity DataIC50: 1.22E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent