BDBM50349194 GLAUCARUBINONE::NSC-14975

SMILES CC[C@](C)(O)C(=O)O[C@@H]1[C@H]2[C@@H](C)[C@@H](O)[C@]3(O)OC[C@@]22[C@H]3[C@]3(C)[C@@H](C[C@H]2OC1=O)C(C)CC(=O)C3=O

InChI Key InChIKey=AHAUNXVCFORDCA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349194   

TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50349194(NSC-14975 | GLAUCARUBINONE)
Affinity DataEC50:  1.49E+3nMAssay Description:Inhibition of AP-1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50349194(NSC-14975 | GLAUCARUBINONE)
Affinity DataEC50:  130nMAssay Description:Inhibition of TPA-induced AP-1 activity expressed in human HEK293T cells treated 1 hr before TPA challenge measured after 18 hrs by FRET based beta-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50349194(NSC-14975 | GLAUCARUBINONE)
Affinity DataIC50: 40nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed