BDBM50404748 CHEMBL19032::NSC-115922

SMILES COc1cc(OC)c2c(c1)oc(-c1ccc(OC)c(OC)c1)c(OC)c2=O

InChI Key InChIKey=ALGDHWVALRSLBT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50404748   

LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 822nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in human 2008 cells assessed as calcein-AM accumulation preincubated for 30 mins before calcein-AM addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50404748(NSC-115922 | CHEMBL19032)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of rat brain particulate cGMP phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed