BDBM50035468 4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-anthracen-1-ylamino)-N,N-bis-(2-hydroxy-ethyl)-benzenesulfonamide::CHEMBL128547::NSC-115290

SMILES OCCN(CCO)S(=O)(=O)c1ccc(Nc2ccc(O)c3C(=O)c4ccccc4C(=O)c23)cc1

InChI Key InChIKey=RWRVDPVYYPGYQI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035468   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035468(NSC-115290 | 4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035468(NSC-115290 | 4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035468(NSC-115290 | 4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-...)
Affinity DataKi:  7.80E+3nMAssay Description:Binding affinity with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed