BDBM203862 6-amino-4-hydroxy-5-[(4-nitro-2-sulfophenyl)azo]-2-naphtalenesulfonic acid disodium salt (Compound 37)::NSC 47703

SMILES Nc1ccc2cc(cc(O)c2c1\N=N\c1ccc(cc1S([O-])(=O)=O)[N+]([O-])=O)S([O-])(=O)=O

InChI Key InChIKey=VCCBSXQXECFSJO-UHFFFAOYSA-L

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203862   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Universidade De Lisboa

LigandPNGBDBM203862(6-amino-4-hydroxy-5-[(4-nitro-2-sulfophenyl)azo]-2...)
Affinity DataIC50: 7.76E+3nMpH: 7.5Assay Description:In this assay, the complementary single-stranded oligonucleotides at 100 m were mixed at a 1:1 ratio and annealed in assay buffer (50 mm Tris pH 7.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Universidade De Lisboa

LigandPNGBDBM203862(6-amino-4-hydroxy-5-[(4-nitro-2-sulfophenyl)azo]-2...)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of recombinant human APE1 using double-stranded DNA as substrate preincubated for 15 mins followed by substrate addition measured at 1 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed